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Teacher Implementation of Research-Based Vocabulary Instruction for Adolescent Learners is a qualitative study of teachers’ response to professional development sessions conveying principles and strategies for vocabulary instruction. The study was supported by a Doing What Works implementation grant funded by the U.S. Department of Education and administered by West Ed, which addressed how to apply research findings contained in the IES practice guide Improving Adolescent Literacy, to professional development of practicing teachers. Participants include science teachers (7), social studies teachers (7) and reading/English language arts teachers (7) from a single junior high school. Teachers indicate the practices they judge to be most effective in their classrooms and specify the supports they need for full implementation of vocabulary instruction.