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The current study examined links between school-level support factors and academic growth in a population of US kindergarteners at-risk of school failure based on demographic characteristics and behavioral functioning. Data from the Early Childhood Longitudinal Study- Kindergarten (ECLS-K) were used to compare reading outcomes of students meeting at-risk criteria and their non-risk peers. School-support factors of interest were family support programs, positive school climate, kindergarten transition programs, and instructional support. Results of HLM analyses indicate a significant positive relationship between instructional support and reading performance across groups, while family support programs are associated with growth among demographically at-risk students and positive school climate with reading growth among students who display behavioral challenges. Implications and future directions will be discussed.