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The individual connections between education, working conditions, work injuries, and mental health have been well documented. Our study connects these distinct phenomena into a single model using a nationally representative longitudinal data set. We find that education acts as a sorting mechanism for determining who takes a hazardous job, and predicts who will sustain a work injury within a job with unsafe conditions. We further find that, despite strong effects of work injuries and early hazardous jobs on later depression, education has a continued impact on depression. Our study looks at long-term outcomes, which gives us a better idea of the extent to which events early in career which are influenced by education can impact later outcomes.