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Research has established the importance of self-regulation skills for young children’s academic success (e.g., McClelland et al., 2007), but more recent work has focused on co-regulation, or ways in which children’s interactions impact their development (e.g., Whitebread et al., 2007; McCaslin, 2009). The current study examined how successful pairs of kindergarteners were on a collaborative problem-solving task. Children were paired based on two factors: 1) whether they were close friends, according to the classroom teacher, and 2) their individual regulatory abilities (e.g., pairing a ‘high-regulated’ child with a ‘low-regulated’ child) Results showed that pairs were less successful on the task if they were identified as close friends by the teacher. Implications for researchers and educators regarding classroom interactions are discussed.