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The current study examined the effect of different sequences of instructional approaches for teaching the distributive principle for multi-digit multiplication. Third graders practiced according to one of four sequences: Algebra-Arithmetic, Algebra-Area, Arithmetic-Algebra, and Area-Algebra. All sequences produced improvements in solving practiced 2D x 2D problems. Critically, the Area-Algebra and Arithmetic-Algebra sequences had the largest effect sizes, with the former better for participants with some prior knowledge of 2D x 2D multiplication and the latter better for participants with no prior knowledge. All sequences produced improvements on transfer tasks, with the Area-Algebra sequence producing the largest improvement for transfer (unpracticed 2D x 2D) problems. Finally, improvements were most associated with prior knowledge of single-digit addition and subtraction – not multiplication – facts.