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Self-directed learning (SDL) is an essential skill for pharmacy students. Over decades, it has been increasingly emphasized in modern pharmacy education programs. In this study, a factor analysis was used to identify the factor structure of a self-rating scale of self-directed learning (SRSSDL) among pharmacy students (n=872) and to examine students’ readiness for SDL by year in the pharmacy educational curriculum. Five factors “Intrinsic motivation”, “Partition”, “Collaboration”, “Reflection” and “Application” showed acceptable levels of reliability. We conclude the revised 55 items SRSSDL is a valid and homogenous scale of pharmacy students’ willingness to engage in self-directed learning within one pharmacy program.