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In this multiple-baseline design study, we examined a 3D, virtual-reality-based social skills training program for the social competency development of children with high-functioning autism. Using OpenSimulator, we constructed a 3D virtual neighbourhood to support both scripted and creative social roleplay, collaborative design quests, and virtual gaming among the target children. Seven 10-14-year-old children with HFASD participated in the VR-based learning program at home. Data were collected via screen recordings of participants’ interactions and actions in the virtual world, onsite observation, and iterative interviews. The current study findings support the feasibility of implementing the VR-based social skills training for participants with HFASD. Participants demonstrated an increased level of social interaction performance and a high level of engagement during the intervention.