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Detecting Publication and Reporting Bias in Multilevel Meta-Analyses: A Simulation Study

Sun, April 7, 8:00 to 9:30am, Metro Toronto Convention Centre, Floor: 200 Level, Room 203A

Abstract

This study explores the performance of classical methods for detecting publication bias, namely Egger’s Regression test, Funnel Plot test, Begg’s Rank Correlation and Trim and Fill method, in meta-analysis of studies that report multiple effects. Publication bias, outcome reporting bias, and a combination of both were generated. Egger’s Regression and Funnel Plot test were extended to three-level models, and possible cutoffs for the L_0^+ estimator of the Trim and Fill method were explored. Furthermore, we checked whether the combination of results of several methods yielded a better control of Type I error rates. Results show that no method works well across all conditions, and that their performance depends mainly on the population effect size value and on the total variance.

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