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Neural and Behavioral Effects of Working Memory Training in Adult Attention Deficit Hyperactivity Disorder: A Randomized Controlled Trial

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Abstract

We investigated the efficacy of an intensive and adaptive computerized working memory training (CWMT) program for college students with Attention-Deficit/Hyperactivity Disorder (ADHD) at behavioral and neural levels. Participants (n=79) were randomized into a Standard-length CWMT, Shortened length CWMT, and a waitlist group. Neural and behavioral indicators of working memory were assessed before and after training. Results showed no evidence of improvement at any level for the CWMT treatment groups over the waitlist group. These findings contribute to the broader literature on neural plasticity with executive function training and provide strong evidence that CWMT is not an effective treatment for college students with ADHD.

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