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The purpose of this paper is to examine the development of humanizing dispositions through a multiple regression analysis of five theoretically based contributing independent variables identified in a framework for teaching. The research question is: How do the observed variables of lovingness, acceptance, hope, courage, and advocacy contribute to the latent trait of humanizing disposition in pre-service teachers? Based on a sample of 230 pre-service teachers, the variables were tested using multiple regression analysis to determine unique attribution to the development of humanizing disposition. Findings reveal a path diagram that illustrates the effects of the variables on the development of humanizing dispositions. This research is significant in that it offers a framework for developing humanizing dispositions in pre-service teaching.