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Guided by a cultural-ecological transactional theoretical framework, the present study sought to build an explanatory and contextualized model of resilience during the transition to college. This model focused on the role of internal coping skills and external supports in shaping trajectories of academic performance and mental health. First year students at a large public university in the United States (n=6614, 80% response rate) completed online surveys prior to matriculation, at the end of the fall quarter and the end of the academic year. Preliminary results suggest better outcomes at year-end among individuals with greater self-compassion and school connectedness, and worse outcomes among sexual minority and first-generation college students. Findings underscore the need for multilevel approaches to supporting entering college students.