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This presentation reports on qualitative case studies of four early career special education teacher who taught literacy to students with (ASD). Formal observations, informal visits, and teacher interviews were conducted with each teacher in order to describe the literacy instruction teachers implemented and identify practices and activities used to enhance the reading comprehension of their students with ASD. The study also looked at the specific differentiated supports teachers use during literacy instruction and challenges teachers encountered. Educators can utilize the findings to help determine strategies and supports, as well as guide future professional development, for developing the literacy skills of students with ASD.