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Abstract: In this study, we propose a mediation model to investigate the potential mediation role of a social network. In the model, the dependence among actors is accounted by a few mutually orthogonal latent dimensions which form a social space. The individuals' positions in such a latent social space directly involve in the intervention process between an independent variable and a dependent variable. To estimate the model, we adopt a Bayesian estimation method. The usefulness of the network mediation model is demonstrated through an empirical application to a friendship network.