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Causal identification of direct and indirect effects requires a stringent, no-unmeasured-mediator-outcome-confounding assumption even when the treatment is randomized. This study develops a difference-in-differences in mediation (DiDiM) approach that extends difference-in-differences methods to mediation. This extension allows causal identification of direct and indirect effects in the presence of unmeasured mediator-outcome confounding. Although this approach requires its own identification assumption, this study also proposes a method to adjust the DiDiM estimators for the bias due to the violation of the key assumption.