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This study (N=1175) examined relationships between mechanisms of teacher education and teacher practices, self-efficacy, and job satisfaction in the U.S. Through secondary analysis of Teaching and Learning International Survey (TALIS) 2018 data, it investigated relations between these important constructs and various pre-service and in-service teacher learning and development activities, formal and informal (e.g., types of professional development, induction, mentoring). Regression analysis adjusted for TALIS’ complex sampling design—and controlling for key teacher socio-demographic and professional characteristics—revealed evidence for the potential value of a variety of teacher-education mechanisms. For instance, we found evidence for the potential benefit of teacher cooperation, particular pre-service teacher education foci, and specific in-service teacher education activities.