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Individuals generally revise their misconceptions when corrected with carefully designed educational materials. However, early reports suggest that correcting COVID-19 misconceptions may be especially challenging, which may be due to conflicts with individuals’ moral values and emotions. The present study explores the mechanisms and boundaries of correction effectiveness. Those highest in moral concerns for group cohesion or for individual freedoms were more likely to affectively or cognitively reject corrective information. Corrections of COVID-19 misconceptions should be carefully framed to connect with the morality of recipients and anticipate their emotional and cognitive reactions.