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Promise Neighborhoods grants aim to offset the long-term impact of families growing up in poverty. This study analyzes applications from 10 funded grants from institutions of higher education (IHEs) (n=5) and non-institutions of higher education (NIHEs) (n=5) from 2016-2018 to determine which factors these neighborhoods plan to address. IHEs and NIHEs are similarly positioned to effectuate change within their communities. The proposed factors and programs reflect the realization of longstanding collaborations with multiple stakeholders, including other anchor institutions, residents, schools, and community leaders. It is necessary for anchor institutions, in coordination with their communities, to plan for long-term sustainability through institutional commitments and leverage community assets to maintain and extend progress beyond the grant.