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Tools for measuring outcomes of interprofessional education (IPE) have been criticized as having weak evidence for validity. The purpose of this study was to examine internal structure for three commonly used self-report tools with data from 684 learners who were enrolled in introductory IPE at four different U.S. universities. The tools demonstrated internal consistency similar to their original validity studies, but there was minor variation in reliability based on whether respondents were traditional college students under the age of 22 or learners age 22 and over. These findings support use of these tools with early learners in IPE and imply that measure selection and inferences may need to be guided by entry-level age of learner and prior healthcare experience.