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Research shows that attrition in STEM majors is higher than other areas and is magnified for low-income and underrepresented students. Though high impact practices - including research, mentoring, professional development, and scholarships - may be effective in improving major retention, research overlooks the impact of combining these practices on student persistence in STEM majors. A study of 29 low-income biology, chemistry, and mathematics majors who participated in a scholarship program providing these high impact practices resulted in 22 (76%) graduating in their original major. This is greater than the comparison group graduation rate (52%), with larger gaps between rates for underrepresented populations. Mixed-methods results are presented along with implications for the structuring of similar programs at large, public, R1, PWIs.