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This study explores children’s development of behavior problems in classroom situations characterized by teacher interactions and structured learning activities during the first four years of schooling. Multidimensional growth mixture modeling was employed to detect unobserved subpopulations (latent classes) with common trajectories of teacher- and learning- context behavior among a US national sample (N = 3,872) of children from low-income backgrounds. Analyses revealed three subpopulations with distinct behavior trajectories that were differentially associated with first-grade academic skills and social-emotional outcomes. Results will be discussed in light of developmental theory and implications for practice.