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A constructivist grounded theory study of purpose and career development was conducted with 59 college students with disabilities. Data explicate the nuanced ways students made meaning of their major/career decisions relative to the constraints imposed by the interaction between their lived disability experiences and a society constructed according to intersecting oppressive (i.e., ableist, racist, classist, sexist, genderist, heterosexist) norms. A grounded model of career decision making is presented.