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In the face of various challenges in the education system, it is crucial for school leaders to enhance organizational conditions to improve teachers' self-efficacy and regulate their emotions. This study examined how school-level factors (i.e., colleague innovation, collaborative teaching, teacher-student relationships, decision making, and school resources) influence teacher self-efficacy and anxiety. Based on 2,873 survey responses from primary teachers in China, the results of structural equation modelling and bootstrapping analysis reveal that collaborative teaching, teacher-student relations, and colleague innovation have a significantly positive influence on teachers′ self-efficacy. Collaborative teaching, school resources, and decision-making have a significantly negative influence on teachers′ anxiety while instructional innovation has a significantly positive influence on teachers′ anxiety.