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The NSF-funded project, Building Education Theory through Enacting Reforms in STEM (BETTER in STEM), employs a unique combination of research-based change strategies to support STEM faculty members’ use of equitable, student-centered instruction in undergraduate STEM courses. Our change strategies and tools, grounded in a novel instructional framework, are designed to maximize impacts and have broad application across STEM disciplines and institutions. Three types of institutions partnered in this work to increase the applicability of the instructional framework, change processes, and corresponding tools to other institutions. The project includes a two-year community college, a mid-size regional university, and a doctoral-granting university that is the second largest Hispanic-serving institution in the country.