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Research shows that professional learning communities (PLCs) foster meaningful professional learning and development for K-12 teachers (McLaughlin & Talbert, 2010). However, the benefits of PLCs for higher education instructors are less well-known (Clark et al., 2023). Responding to this research and practice opportunity, we formed a research practice partnership (RPP) with six college composition instructors at a large, land-grant institution in the Midwest. Adopting a design-based research (DBR) methodology to facilitate collaboration among researchers and participants, the RPP took the shape of a PLC, focused on integrating human-centered design (HCD) in college composition courses. Findings suggest that a PLC in a university context facilitates instructors’ ability to address problems of practice through collaborative co-design of instructional plans.