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Reading achievement declined drastically during the COVID-19 pandemic. Closing the COVID gap and accelerating learning has been a priority; it is essential to identify and implement evidence-based programs and interventions that can meet these goals. Recent emphasis on the science-of-reading provide further impetus. Prior efficacy studies have shown positive impacts of Enhanced Core Reading Instruction (ECRI), a comprehensive approach to early reading instruction and intervention, on broad measures of students’ reading outcomes. We present two years of results of a rigorous randomized controlled trial examining the effectiveness of ECRI under routine implementation conditions on the foundational reading skills of first-grade students with or at risk for reading disabilities.