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Efforts to increase student interest in science are complicated by the limited amount of instructional time dedicated to the subject. One possible solution for encouraging more students to pursue science is to develop integrated curricula that weave science and other topics together. We explain how teachers’ prior knowledge and experiences using technology impact their ability to implement an online educational environment. TPACK framework was used to learn, what elements of a teacher’s TPACK influence their implementation of a technological learning environment designed to support the integration of computational thinking, narrative, and science instruction. We found teachers who used more pedagogical strategies had an easier time using the online learning platform. Therefore, professional learning should support teachers’ development of TPACK.