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Our study explored sibling-mediated video-based instruction to support autistic youth’s independent living skills using a single case, multiple probe design across three 13-19 year old autistic youth and their 9-15 year old siblings. After two researcher-led zoom training sessions, siblings used video-based instruction with a system of least to most supportive prompts and reinforcement to support their autistic sibling. A visual analysis of the graphed data was conducted to evaluate the trend, level, stability, and immediacy of effect across the three families which demonstrated a functional relation (or positive effect) between the sibling-mediated instruction and autistic youth’s percentage of correct steps to complete their selected independent living skills (e.g., using Excel, wiping the table, loading the dishwasher).