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International Science Teachers and Teacher Candidates (ISTCs) often encounter multiple deficit views that hinder their strength and effectiveness in teacher education. The literature largely portrays ISTCs through a lens of linguistic and cultural deficits, overlooking their potential contributions. This study aims to develop a Transformative Empowerment Framework for ISTCs (TEFI) that shifts the narrative from a deficit to a more agentive and active perspective, which employs Transformative Activist Stance (TAS), Standpoint Theory, Indigenous Knowledge Theory, Belongingness and Care theory to develop a bricolage theoretical framework. The framework was integrated into a graduate-level science education pedagogy course. Evidence shows that the framework effectively challenged and began to transform the entrenched deficit stance both internally among ISTCs and externally among educational stakeholders.