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Highlighting the increased adoption of technology-based cognitive assessments, recent literature underscores the need to examine how test-takers’ response processes influence item functioning. This study investigates the critical relationship between variations in test-takers item response processes and item success, conditioned on test-takers’ abilities and demographic backgrounds. Utilizing machine learning methods and a generalized linear modeling (GLM) approach, this study proposes a measure to identify differential effects of process functioning (DEPF), which arise from the deviations in test-takers’ response process due to demographic differences and affects the overall item success probability for specific groups. The results suggested that variations in response processes may reveal fairness issues in technology-based items, as certain item components could disadvantage specific groups of test-takers.