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Women remain underrepresented in science, technology, engineering, and mathematics (STEM) fields. This study explored the relation between girls' performance on an 8th-grade mathematics Texas Assessment of Knowledge and Skills (TAKS) and later completion of STEM degrees to identify a practical way to close the gender gap. We used logistic regression on degree completers at a diverse university in Texas (N = 5,264) to calculate the odds of women completing STEM degrees based on mathematics scale scores. There was a positive association between mathematics scores and STEM degree completion, highlighting the influence of 8th-grade mathematics scores on women's educational and career pathways. The findings suggest the potential benefits of interventions during adolescence to enhance mathematical competencies.