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This study investigates the impact of careless respondents on the estimation of category-level guess and slip parameters in the sequential-GDINA (s-GDINA) model using Monte Carlo simulations. Four types of careless response patterns were examined: random carelessness, acquiescence, long-string responses, and mixed types. Data were simulated under 24 conditions with varying proportions of careless respondents (5% to 50%). Results showed that increasing careless response rates led to higher RMSE values, especially for slip parameters. Acquiescence responses caused the greatest bias, while long-string responses had the least effect. These findings highlight the vulnerability of s-GDINA parameter estimates to careless responding and underscore the need for further research on detection methods within cognitive diagnostic modeling frameworks.