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We aimed to examined the relationship between anxiety and bedtime procrastination among college students, with particular attention to the mediating roles of self-control and mobile phone dependence. Results based on a group of 393 Chinese colleges students revealed that both self-control and mobile phone dependence independently and fully mediated the relationship between anxiety and bedtime procrastination. Additionally, a sequential mediation effect was observed as anxiety indirectly predicted greater bedtime procrastination through decreased self-control and, subsequently, increased mobile phone dependence. Findings of the present study suggest that failure to cope with emotional dysregulation may contribute to bedtime procrastination, highlighting the importance of promoting adaptive self-regulatory strategies to foster resilience and important intervention targets for improving sleep-related behaviors in the college populations.