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This study examines the relationships among cultural values, psychological resilience, and depression in 1,497 Taiwanese high school students. Guided by an adaptation-based framework, four learned attributes—secure attachment, self-compassion, self-efficacy, and experience-connection—were proposed to influence resilience and depression. Structural equation modeling (SEM) showed that all four attributes positively predicted resilience and negatively predicted depression, with resilience partially mediating these effects. Multiple regression analyses revealed that long-term orientation and collectivism promoted resilience, while long-term orientation reduced depression. However, both collectivism and power distance were linked to higher depression. These findings underscore the cultural shaping of resilience and mental health in adolescents and support the development of culturally responsive interventions. Specific strategies will be discussed in the presentation and future work.