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This study examines predictors of faculty's artificial intelligence (AI) integration in higher education, with a particular focus on the mediating role of anxiety. We employed a cross-sectional survey design with 170 educators from U.S. post-secondary institutions. Path analysis revealed that institutional support significantly predicted greater AI integration (β = 0.241, p = .001) and reduced anxiety about AI use (β = -0.273, p = .001). Anxiety mediated this relationship, accounting for 31.3% of the total effect (β = 0.110, p = .008), while demonstrating a strong negative association with integration (β = -0.401, p < .001). These findings highlight the importance of addressing emotional and psychological barriers alongside providing technical support for holistic faculty development programs that factor anxiety-reduction strategies.