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This study explores the relationship between self-leadership and core competencies within a competency-based education (CBE) framework among university students. Using Latent profile analysis, three distinct self-leadership profiles (low, moderate, and high) were identified. Then, network analysis revealed students with higher self-leadership demonstrated more interconnected and integrated competency structures, with convergence emerging as a central node. Significant differences were found across profiles in levels of integrated thinking, knowledge inquiry, global leadership, self-management, and convergence. These findings underscore the role of self-leadership in fostering adaptive, autonomous learning and highlight the potential of network analysis as a diagnostic tool. Implications for curriculum design and instructional practices are discussed to promote student agency and holistic competency development in higher education.