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The Trump administration’s funding cuts and policy shifts threaten evidence-based improvement in high-needs schools and place the U.S. public education system at risk. To inform the current policy debate, this study conducts comparative meta-analysis of research evidence on the efficacy and equity outcomes of different educational interventions, including major federal, state and local policies/programs. Applying meta-analysis methods to P-12 education policy typologies, the study systematically compares the effects of targeted vs. universal, input/process-driven vs. output/performance-driven, and community-based vs. market-based intervention approaches. The results provide relatively strong support for targeted, input/process-driven, and community-based intervention approaches that better help advance the twofold goals of excellence and equity: improving student achievement overall while closing achievement gaps among racial and/or socioeconomic groups of students.