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This paper introduces proposition testing, a structured, team-based method for achieving iterative integration that yields robust conclusions in mixed methods research. In contrast to common approaches that present qualitative and quantitative data in parallel, proposition testing fosters sustained dialogue between strands to refine interpretive claims. Drawing on grounded theory, multiple case study, and constant comparison, the process involves generating, challenging, and revising propositions across multiple rounds of analysis. We illustrate the method’s application across several empirical studies, including traditional and less conventional mixed methods designs. By promoting analytic rigor, transparency, and collaboration, proposition testing offers a practical strategy for enhancing integration and maximizing the contributions of diverse data sources in addressing complex research questions.