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This study investigates determinants of academic success in an introductory psychology statistics course using ensemble machine learning methods. Survey data from 186 undergraduates at a Hispanic-Serving Institution were linked to institutional grade records. Variables included statistics anxiety, statistics self-efficacy, demographics, and perceptions of relevance. Using ensemble techniques combining Least Absolute Shrinkage and Selection Operator (LASSO), random forest, and stepwise regression, the analysis identified statistics self-efficacy and anxiety as the most impactful predictors of course grades. Notable group differences emerged across gender and race. These findings highlight the utility of machine learning for educational research and underscore the role of psychological factors in statistics performance, with implications for instruction and student support.