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This study proposes and validates an integrated competence model linking AI literacy, TPACK, and the Community of Inquiry (CoI) within the IMTPG framework. Drawing on data from pre-service STEM teachers, the model identifies three key pathways: affective literacy as a foundation shaping cognitive, behavioral, and ethical literacy; cognitive literacy enhancing TPACK-based teaching competence; and behavioral and ethical literacy supporting student-centered learning through social and cognitive presence. The findings offer theoretical and practical insights into how pre-service teachers transform AI-related knowledge into instructional competence and foster meaningful learning in AI-enhanced environments.