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Specifying Weakly Informative Priors in Bayesian Meta-Analysis

Thu, April 9, 7:45 to 9:15am PDT (7:45 to 9:15am PDT), Los Angeles Convention Center, Floor: Level Two, Poster Hall - Exhibit Hall A

Abstract

In small-sample meta-analysis, Bayesian random-effects models often yield credible intervals for parameters of interest that are overly conservative. This study introduces a data-driven approach to specify a weakly informative prior distribution for the heterogeneity parameter aiming to alleviate the wide intervals obtained from Bayesian random-effects models. The findings from empirical data analysis and simulation study show that an inverse-gamma prior with the mode set to the maximum likelihood estimate of the between-study variance yields credible intervals that are close to the nominal 95% coverage. The near-nominal coverage rate remains consistent across various simulation settings, suggesting that this alternative approach offers a plausible range of values for the heterogeneity parameter in small-sample situations.

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