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This study explores how high school students develop an understanding of complex systems through a curriculum centered on the Venus flytrap. The curriculum integrates biology, physics, and engineering concepts, using multiple external representations (MERs), such as a living plant electrophysiology experiment, an agent-based model, and a Rube Goldberg machine. A mixed-methods approach assessed students’ understanding of complex systems characteristics like emergence, non-linear interactions, and adaptation. Findings suggest students were able to connect complex systems principles to the flytrap, transfer their understanding to real-world scenarios, and recognize the value of STEM-integrated learning. This research highlights the potential of MERs in supporting systems thinking and emphasizes the role of complex systems education in enhancing high school students’ engagement with real-world science.