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This study explores the qualities and processes of an out-of-school, extramural program in STEM-Medicine that fosters an environment composed of college socialization for high school students, which we term a ‘culture of transformation.’ Drawing on theory of validation (Rendón, 1994), we argue that students with marginalized identities with respect to race, gender, and class are beneficiaries of a cultivated culture of transformation, which signals important interventions for historical forms of social inequities in STEM-M and society writ large. Using a multi-year study (2016-2019), we examined 72 interviews and conducted in-depth qualitative analysis with six cohorts of students (N=37). We found that participants leverage their engagement with 1) equitable resources, 2) relevant opportunities, 3) diverse knowledge, and 4) meaningful relationships.