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This research aims to examine the quality of interpersonal relationships (QIR) in connection with the satisfaction and thwarting of basic psychological needs (BPNs) among employees in school settings. Three studies were conducted. Study 1 (n=266 staff members) and Study 2 (n=300 teachers) show that the QIR with administration and colleagues is positively associated with BPNs satisfaction and negatively with BPNs thwarting. Study 3 (n=180 teachers) aimed to replicate the findings of Studies 1 and 2 using a prospective design. Results provided partial support for the model: the QIR with administration is negatively associated with BPNs thwarting (competence, autonomy); the QIR with colleagues is positively associated with BPNs satisfaction (relatedness, competence, autonomy) and negatively associated with BPNs thwarting (competence, autonomy).