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This meta-analysis study reviews and synthesizes research and evaluation findings demonstrating the effects of integrating innovative technologies and technology-based learning experiences in STEM education on K-12 students’ STEM career-related outcomes. This study synthesizes a body of research from 1995 to the present, across characteristics of technology-based STEM education interventions, learning contexts, student demographics, and study designs. This study develops an understanding of the extent to which the effects of technology-based STEM education interventions are different for students who are traditionally underserved and underrepresented in STEM education. Findings suggest such interventions have small, positive effects on students’ STEM career outcomes. Interventions serving underrepresented students had larger influences on students’ career outcomes than those serving general student populations.