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This paper analyzes the dynamics of a neglected institution whose importance became clear during the COVID-19 pandemic: the scientific advisory committee. What I call “the paradox of scientific advice” consists in the fact that the two basic expectations from scientific advice—neutrality and usefulness—are inherently in tension. To be useful, advisors must help decision makers set and attain their goals. Judgments about values and ends are necessary for useful advice, as are subjective judgments in the face of uncertainty and disagreement. This puts the committee in a double bind: if it tries to be more useful, it compromises the neutrality that is the source of its authority and legitimacy; if it tries to remain neutral, it sacrifices usefulness. I argue that this dilemma cannot be solved within the committee but that broader democratic scrutiny could mitigate its force. Advisory committees, in turn, should be structured to facilitate this scrutiny.