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Migration remains a focal point of American policy, with the United States serving as a primary destination for individuals seeking residency. Latino migrants, in particular, encounter significant stressors related to their migration experience, socioeconomic positioning, and cultural adaptation. While previous research has extensively documented the negative health outcomes associated with stress, less is known about the protective role of social engagement in mitigating stress among Latino migrants. This study examines how different forms of social engagement—contact with family and friends and participation in civil society networks—moderate stress experiences among Latino migrants in the U.S. Findings indicate that participation in civil society networks significantly reduces stress, particularly among millennials and male respondents. However, frequent contact with family and friends has differential effects, with generational and ethnic subgroup variations shaping the relationship. These results highlight the complexities of social engagement and its role in stress modulation among Latino migrants, offering insights into how social networks can function as both protective and stress-inducing factors.