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This paper examines the relationship between residential segregation and disability among Dominicans—a minority group with one of the highest racial and class segregation in the U.S. We ask if county-level segregation affects the probability of individual-level disability, and if socioeconomic status (SES) mediates the relationship between segregation and disability. We merge individual-level data from the 2026 American Community Survey with county-level data from the 2020 U.S. Census. Multilevel analyses reveal that SES mediates the relationship between segregation and disability, as suggested by Racialized Place Inequality Framework (RPIF). We conclude with policy implications for housing and disability among ethno-racial minorities.