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The debate about the use of restrictive housing has focused, in part, on whether the practice causes psychological harm to the individuals in confinement. This paper will discuss the current state of empirical knowledge about the relationship between mental health and restrictive housing. It will address the overall psychological effects of restrictive housing and the effect of particular characteristics of confinement (e.g., the purpose, duration, and physical conditions) and characteristics of the individual (e.g., age, gender, cognitive ability, pre-existing mental illness) on psychological functioning. The author will discuss research and policy recommendations.