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Persistent and serious involvement in drug use and drug selling has powerful negative ramifications in multiple life domains, including the family, employment, and experiences with the criminal justice system. Using longitudinal data from the Rochester Youth Development Study, previous research has shown that factor analysis can be used to develop empirical typologies of drug-related behaviors in adolescence, and that those typologies are predictive of arrests at multiple points in the life course. The current study extends that work to determine if such typologies are predictive of family and employment indicators at the same points in the life course, drawing from Interactional Theory to guide empirical analyses and evaluate conclusions. Results from this study will help determine the magnitude and duration of drug-related behaviors' impacts on the successful transition from adolescence to adulthood.