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Recent scholarship suggests treatment effects from cognitive-behavioral therapy (CBT) programs can significantly reduce rates of prison misconduct. However, this may not be a full accounting of CBT effects, due in part to publication bias towards positive results and the limitations of non-experimental research designs. This study utilizes a quasi-experimental methodology to evaluate the effectiveness of a CBT-based substance abuse program in reducing misconduct at a northeastern correctional facility. Disciplinary reports were compared as an outcome between program graduates (n=158) and non-graduates (n=483) using propensity score matching. Results indicated no significant treatment effects on misconduct. Implications for research and correctional policy are discussed.